Publications

2021

Nuber F., Schimpf J., di Rago J.P., Tribouillard-Tanvier D., Procaccio V., Martin-Negrier M.L., Trimouille A., Biner O., von Ballmoos C. & Friedrich T. (2021) Biochemical consequences of two clinically relevant ND-gene mutations in Escherichia coli respiratory complex I. Sci Rep. 2021 Jun, doi: 10.1038/s41598-021-91631-3

2020

Amati A.M., Graf S., Deutschmann S., Dolder N., von Ballmoos C. (2020) Current problems and future avenues in proteoliposome research. Biochem Soc Trans. 2020 Aug, doi: 10.1042/BST20190966

Bruggisser J., Tarek B., Wyder M., Müller P., von Ballmoos C., Witz G., Enzmann G., Deutsch U., Engelhardt B., Posthaus H. (2020) CD31 (PECAM-1) Serves as the Endothelial Cell-Specific Receptor of Clostridium perfringens β-Toxin. Cell host & microbe Jun 2020, doi: 10.1016/j.chom.2020.05.003

Dolder N., von Ballmoos C. (2020) Bifunctional DNA duplexes permit efficient incorporation of pH probes into liposomes. ChemBioChem. 2020 Mar, doi: 10.1002/cbic.202000146

Toth A., Meyrat A., Stoldt S., Santiago R., Wenzel D., Jakobs S., von Ballmoos, C., Ott M. (2020) Kinetic coupling of the respiratory chain with ATP synthase, but not proton gradients, drives ATP production in cristae membranes. PNAS Jan 2020, doi: 10.1073/pnas.1917968117

2019

Graf, S., Brzezinski, P., (2019) von Ballmoos, C. The proton pumping bo oxidase from Vitreoscilla. Sci Rep. 2019 Mar 18;9(1):4766. doi: 10.1038/s41598-019-40723-2

Meyrat, A., von Ballmoos, C. (2019) ATP synthesis at physiological nucleotide concentrations. Sci Rep. 2019 Feb 28;9(1):3070. doi: 10.1038/s41598-019-38564-0

2018

Lundgren, C. A. K., Sjöstrand, D., Biner, O., Bennett, M., Rudling, A., Johansson, AL., Brzezinski, P., Carlsson, J., von Ballmoos, C. & Högbom, M. (2018) Scavenging of superoxide by a membrane-bound superoxide oxidase. Nat Chem Biol. 2018 Jun 18. doi: 10.1038/s41589-018-0072-x [Epub ahead of print]

Biner, O., Schick, T., Ganguin, A. A., & von Ballmoos, C. (2018) Towards a Synthetic Mitochondrion. CHIMIA International Journal for Chemistry, 72(5), 291–296. doi: 10.2533/chimia.2018.291

2017

Belevich, N., von Ballmoos, C., Verkhovskaya, M. (2017) Activation of Proton Translocation by Respiratory Complex I. Biochemistry. 2017 Oct 24;56(42):5691-5697. doi: 10.1021/acs.biochem.7b00727. Epub 2017 Oct 12.

Sjöholm, J., Bergstrand, J., Nilsson, T., Šachl, R., Ballmoos, C. V., Widengren, J., & Brzezinski, P. (2017) The lateral distance between a proton pump and ATP synthase determines the ATP-synthesis rate. Scientific reports, 7(1), 2926. http://doi.org/10.1038/s41598-017-02836-4

Poiana, F., von Ballmoos, C., Gonska, N., Blomberg, M. R. A., Ädelroth, P., & Brzezinski, P. (2017) Splitting of the O–O bond at the heme-copper catalytic site of respiratory oxidases. Science Advances, 3(6), e1700279. http://doi.org/10.1126/sciadv.1700279

Uzdavinys P., Coinçon M., Nji E., Ndi M., Winkelmann I., von Ballmoos C., Drew D. (2017) Dissecting the proton transport pathway in electrogenic Na+/H+ antiporters. Proc Natl Acad Sci U S A. 2017 Feb 1. pii: 201614521. doi: 10.1073/pnas.1614521114. [Epub ahead of print]

von Ballmoos, C., Smirnova, I., Poiana, F., Gonska, N., Chang, H.-Y., Gennis, R. B., Brzezinski, P. and Ädelroth, P. (2017) Dynamics of the KB Proton Pathway in Cytochrome ba3 from Thermus thermophilus. Isr. J. Chem.. doi:10.1002/ijch.201600136

2016

Graf S., Fedotovskaya O., Kao WC., Hunte C., Ädelroth P., Bott M., von Ballmoos C., Brzezinski P. (2016) Rapid Electron Transfer within the III-IV Supercomplex in Corynebacterium glutamicum. Scientific reports, 2016 Sep 29;6:34098. doi: 10.1038/srep34098

Smirnova IA., Sjöstrand D., Li F., Björck M., Schäfer J., Östbye H., Högbom M., von Ballmoos C., Lander GC., Ädelroth P., Brzezinski P. (2016) Isolation of yeast complex IV in native lipid nanodiscs. Biochim Biophys Acta., 2016 Sep 13;1858(12):2984-2992. doi: 10.1016/j.bbamem.2016.09.004. [Epub ahead of print]

Rydström Lundin C., von Ballmoos C., Ott M., Ädelroth P., Brzezinski P. (2016) Regulatory role of the respiratory supercomplex factors in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A., 2016 Aug 2;113(31):E4476-85. doi: 10.1073/pnas.1601196113. Epub 2016 Jul 18.

Biner O., Schick T., Müller Y., von Ballmoos C. (2016) Delivery of membrane proteins into small and giant unilamellar vesicles by charge-mediated fusion. FEBS Letters, 2016 Jul;590(14):2051-62. doi: 10.1002/1873-3468.12233. Epub 2016 Jun 21.

Nilsson T., Lundin CR., Nordlund G., Ädelroth P., von Ballmoos C., Brzezinski P. (2016) Lipid-mediated Protein-protein Interactions Modulate Respiration-driven ATP Synthesis. Scientific reports, 2016 Apr 11;6:24113. doi: 10.1038/srep24113.

2015

von Ballmoos C. , Biner O., Nilsson T., Brzezinski P. (2015) Mimicking respiratory phosphorylation using purified enzymes. Biochim Biophys Acta , Epub before print doi: 10.1016/j.bbabio.2015.12.007

Biner O., Trachsel C., Moser A., Kopp L., Langenegger N., Kämpfer U., von Ballmoos C. , Nentwig W., Schürch S., Schaller J., Kuhn-Nentwig L. (2015) Isolation, N-glycosylations and Function of a Hyaluronidase-Like Enzyme from the Venom of the Spider Cupiennius salei. PLoS One, 10(12):e0143963.

Lindholm L., Ariöz C., Jawurek M., Liebau J., Mäler L., Wieslander Å., von Ballmoos C. , Barth A. (2015) Effect of lipid bilayer properties on the photocycle of green proteorhodopsin. Biochim Biophys Acta 1847, 698-708.

von Ballmoos C. , Gonska N., Lachmann P., Gennis R.B., Ädelroth P., Brzezinski P. (2015) Mutation of a single residue in the ba3 oxidase specifically impairs protonation of the pump site. Proceedings of the National Academy of Sciences of the United States of America 112, 3397-402.

2014

Lee, C., Yashiro, S., Dotson, D. L., Uzdavinys, P., Iwata, S., Sansom, M. S. P., von Ballmoos, C., Beckstein, O., Drew, D., and Cameron, A. D. (2014) Crystal structure of the sodium–proton antiporter NhaA dimer and new mechanistic insights, The Journal of General Physiology 144, 529-544.

Nordlund, G., Brzezinski, P., and von Ballmoos, C. (2014) SNARE-fusion mediated insertion of membrane proteins into native and artificial membranes. Nature communications 5, 4303.

2013

Smirnova, I., Chang, H. Y., von Ballmoos, C., Adelroth, P., Gennis, R. B., and Brzezinski, P. (2013) Single mutations that redirect internal proton transfer in the ba3 oxidase from Thermus thermophilus, Biochemistry 52, 7022-7030.

Lee, C., Kang, H. J., von Ballmoos, C., Newstead, S., Uzdavinys, P., Dotson, D. L., Iwata, S., Beckstein, O., Cameron, A. D., and Drew, D. (2013) A two-domain elevator mechanism for sodium/proton antiport, Nature 501, 573-577.

Gigliobianco, T., Gangolf, M., Lakaye, B., Pirson, B., von Ballmoos, C., Wins, P., and Bettendorff, L. (2013) An alternative role of FoF1-ATP synthase in Escherichia coli: synthesis of thiamine triphosphate, Scientific reports 3, 1071.

Oliynyk, V., Mille, C., Ng, J. B., von Ballmoos, C., Corkery, R. W., and Bergstrom, L. (2013) Selective and ATP-driven transport of ions across supported membranes into nanoporous carriers using gramicidin A and ATP synthase, Physical chemistry chemical physics : PCCP 15, 2733-2740.

2012

von Ballmoos, C., Lachmann, P., Gennis, R. B., Adelroth, P., and Brzezinski, P. (2012) Timing of electron and proton transfer in the ba(3) cytochrome c oxidase from Thermus thermophilus, Biochemistry 51, 4507-4517.

Ojemyr, L. N., von Ballmoos, C., Faxen, K., Svahn, E., and Brzezinski, P. (2012) The membrane modulates internal proton transfer in cytochrome c oxidase, Biochemistry 51, 1092-1100.

Nasvik Ojemyr, L., von Ballmoos, C., Gennis, R. B., Sligar, S. G., and Brzezinski, P. (2012) Reconstitution of respiratory oxidases in membrane nanodiscs for investigation of proton-coupled electron transfer, FEBS letters 586, 640-645.

von Ballmoos, C., Adelroth, P., Gennis, R. B., and Brzezinski, P. (2012) Proton transfer in ba(3) cytochrome c oxidase from Thermus thermophilus, Biochimica et biophysica acta 1817, 650-657.

2011

von Ballmoos, C., Gennis, R. B., Adelroth, P., and Brzezinski, P. (2011) Kinetic design of the respiratory oxidases, Proceedings of the National Academy of Sciences of the United States of America 108, 11057-11062.

2010

Smirnova, I., Reimann, J., von Ballmoos, C., Chang, H. Y., Gennis, R. B., Fee, J. A., Brzezinski, P., and Adelroth, P. (2010) Functional role of Thr-312 and Thr-315 in the proton-transfer pathway in ba3 Cytochrome c oxidase from Thermus thermophilus, Biochemistry 49, 7033-7039.

2009

von Ballmoos, C., Wiedenmann, A., and Dimroth, P. (2009) Essentials for ATP synthesis by F1F0 ATP synthases, Annual review of biochemistry 78, 649-672.

Seeger, M. A., von Ballmoos, C., Verrey, F., and Pos, K. M. (2009) Crucial role of Asp408 in the proton translocation pathway of multidrug transporter AcrB: evidence from site-directed mutagenesis and carbodiimide labeling, Biochemistry 48, 5801-5812.

Wiedenmann, A., Dimroth, P., and von Ballmoos, C. (2009) Functional asymmetry of the F(0) motor in bacterial ATP synthases, Molecular microbiology 72, 479-490.

2008

Wiedenmann, A., Dimroth, P., and von Ballmoos, C. (2008) Deltapsi and DeltapH are equivalent driving forces for proton transport through isolated F(0) complexes of ATP synthases, Biochimica et biophysica acta 1777, 1301-1310.

von Ballmoos, C., Cook, G. M., and Dimroth, P. (2008) Unique rotary ATP synthase and its biological diversity, Annual review of biophysics 37, 43-64.

Vorburger, T., Ebneter, J. Z., Wiedenmann, A., Morger, D., Weber, G., Diederichs, K., Dimroth, P., and von Ballmoos, C. (2008) Arginine-induced conformational change in the c-ring/a-subunit interface of ATP synthase, The FEBS journal 275, 2137-2150.

Seeger, M. A., von Ballmoos, C., Eicher, T., Brandstatter, L., Verrey, F., Diederichs, K., and Pos, K. M. (2008) Engineered disulfide bonds support the functional rotation mechanism of multidrug efflux pump AcrB, Nature structural & molecular biology 15, 199-205.

Dimroth, P., and von Ballmoos, C. (2008) ATP synthesis by decarboxylation phosphorylation, Results and problems in cell differentiation 45, 153-184.

2007

von Ballmoos, C. (2007) Alternative proton binding mode in ATP synthases, Journal of bioenergetics and biomembranes 39, 441-445.

von Ballmoos, C., and Dimroth, P. (2007) Two distinct proton binding sites in the ATP synthase family, Biochemistry 46, 11800-11809.

2006

Dimroth, P., von Ballmoos, C., and Meier, T. (2006) Catalytic and mechanical cycles in F-ATP synthases. Fourth in the Cycles Review Series, EMBO reports 7, 276-282.

2004

von Ballmoos, C., and Dimroth, P. (2004) A continuous fluorescent method for measuring Na+ transport, Anal Biochem 335, 334-337.

Xing, J., Wang, H., von Ballmoos, C., Dimroth, P., and Oster, G. (2004) Torque generation by the Fo motor of the sodium ATPase, Biophysical journal 87, 2148-2163.

von Ballmoos, C., Brunner, J., and Dimroth, P. (2004) The ion channel of F-ATP synthase is the target of toxic organotin compounds, Proceedings of the National Academy of Sciences of the United States of America 101, 11239-11244.

2003

Dimroth, P., von Ballmoos, C., Meier, T., and Kaim, G. (2003) Electrical power fuels rotary ATP synthase, Structure 11, 1469-1473.

Cook, G. M., Keis, S., Morgan, H. W., von Ballmoos, C., Matthey, U., Kaim, G., and Dimroth, P. (2003) Purification and biochemical characterization of the F1Fo-ATP synthase from thermoalkaliphilic Bacillus sp. strain TA2.A1, Journal of bacteriology 185, 4442-4449.

Meier, T., von Ballmoos, C., Neumann, S., and Kaim, G. (2003) Complete DNA sequence of the atp operon of the sodium-dependent F1Fo ATP synthase from Ilyobacter tartaricus and identification of the encoded subunits, Biochimica et biophysica acta 1625, 221-226.

Meier, T., Matthey, U., von Ballmoos, C., Vonck, J., Krug von Nidda, T., Kuhlbrandt, W., and Dimroth, P. (2003) Evidence for structural integrity in the undecameric c-rings isolated from sodium ATP synthases, Journal of molecular biology 325, 389-397.

2002

von Ballmoos, C., Meier, T., and Dimroth, P. (2002) Membrane embedded location of Na+ or H+ binding sites on the rotor ring of F1F0 ATP synthases, European journal of biochemistry / FEBS 269, 5581-5589.

von Ballmoos, C., Appoldt, Y., Brunner, J., Granier, T., Vasella, A., and Dimroth, P. (2002) Membrane topography of the coupling ion binding site in Na+-translocating F1F0 ATP synthase, The Journal of biological chemistry 277, 3504-3510.